Thesis
Skin-related
Hydrogen Clearance: Technical Evaluation for Measuring Skin Flap Blood Flow in Pigs
Hydrogen clearance technique was evaluated for measuring skin flap blood flow in a pig model. This method assesses blood flow by detecting changes in hydrogen concentration within tissues. Results confirmed that hydrogen clearance can accurately and reliably measure skin flap blood flow in pigs. Compared to conventional blood flow measurement methods, it demonstrated high accuracy and reproducibility, suggesting it could be a useful tool for non-invasive blood flow assessment in skin flaps.
1991, Division of Plastic Surgery, Royal Victoria Hospital, Montreal, Quebec, Canada.
Comparison of Hydrogen Clearance with Laser Doppler Fluxmetry and Thermal Diffusion Methods for Measuring Skin Blood Flow
This study compared Laser Doppler Fluxmetry (LDF) and the Thermal Diffusion Method (TDM) with the Hydrogen Clearance technique for measuring skin blood flow. LDF uses lasers to assess surface blood flow, while TDM evaluates blood flow through skin temperature variations. Findings indicate that both methods effectively measure skin blood flow, but differences exist in accuracy and reliability. Compared to hydrogen clearance, LDF demonstrated higher accuracy and consistency, suggesting it may be a more effective technique for skin blood flow evaluation.
2019, Institute of Medical and Dental Engineering, Tokyo Medical and Dental University, Japan.
PBMT for the Prevention of Acute Radiation Dermatitis: A Systematic Review and Meta-Analysis
PBMT was found to significantly reduce skin damage, decrease inflammation, and promote skin regeneration in patients undergoing radiation therapy, lowering the incidence of acute radiation dermatitis. PBMT may be a promising preventive adjunct therapy for these patients.
March 2023, Sidra Medicine, Department of Surgery, Doha, Qatar; Weill Cornell Medicine, New York & Qatar
PBMT: Systematic Review on the Tumor Safety of Low-Level Light Therapy (LLLT) for Aesthetic Skin Rejuvenation
Evidence suggests that LLLT enhances skin regeneration, improves wrinkles, and promotes collagen synthesis without increasing tumor risk. LLLT may be an effective cosmetic treatment while maintaining tumor safety.
October 2023, Sidra Medicine, Department of Surgery, Doha, Qatar; Weill Cornell Medicine, New York & Qatar
Evaluating the Effect of PBMT in Preventing Acute Radiation Dermatitis in Breast Cancer Patients through Physiological Skin Measurements
PBMT reduced radiation-induced skin damage, improved moisture content, elasticity, and blood flow, and decreased inflammation. It may be a promising adjunct therapy for preventing acute radiation dermatitis in breast cancer patients.
April 2019, Hasselt University, Faculty of Medicine and Life Sciences, Hasselt, Belgium; Jessa Hospital, Department of Medical Oncology, Hasselt, Belgium
Penetration Profile of Class IV Therapeutic Lasers and PBMT Devices in Equine Skin
Both Class IV therapeutic lasers and PBMT devices demonstrated effective penetration in horse skin.
February 2020, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil; Faculty of Veterinary Medicine and Animal Science (FMVZ); Integrated Animal Health Center, Salt Spring Island, British Columbia, Canada
Low-Intensity Visible and Near-Infrared Light-Induced Skin Cell Signaling Pathways: A Comprehensive Review
Low-intensity PBMT increases ATP production, regulates reactive oxygen species (ROS), and activates various cellular signaling pathways, leading to collagen synthesis, reduced inflammation, and enhanced cell proliferation and migration.
April 2023, Laval University, Quebec City, Quebec, Canada; Quebec University Hospital, Faculty of Medicine, Clinical and Biomedical Sciences Graduate Program
PBMT's Effects on Tumor Necrosis Factor-Alpha (TNF-α) in Random Skin Flap Survival: A Rat Model Study
PBMT may be a promising adjunct therapy to enhance postoperative recovery and improve skin flap surgery success rates.
April 2022, State University of Paraíba (UEPB), Graduate Program in Dentistry, Campina Grande, Paraíba, Brazil; Federal University of São Carlos, Department of Physiotherapy, São Carlos, São Paulo, Brazil
Effects of Red LED PBMT on Inflammatory Cells During Skin Burn Healing
Red LED PBMT significantly reduced inflammatory cell numbers and activity, alleviated the inflammatory response, and accelerated wound healing. PBMT may be a promising adjunct for burn treatment.
September 2022, State University of Paraíba (UEPB), Graduate Program in Dentistry, Campina Grande, Paraíba, Brazil; Federal University of São Carlos, Department of Physiotherapy, São Carlos, São Paulo, Brazil
PBMT Enhances Energy-Based Integration and Remodeling in Skin Transplantation in an Ex Vivo Human Skin Model
PBMT may be a promising adjunct therapy to improve postoperative recovery and increase the success rates of skin grafting procedures.
September 2018, Federal University of São Carlos, Department of Gerontology, Laboratory of Aging Biology (LABEN), São Carlos, São Paulo, Brazil; Department of Physiotherapy, Federal University of São Carlos, São Carlos, São Paulo, Brazil
Enhancing Skin Microcirculation Through PBMT Mechanisms Beyond Photothermal Effects Using Low-Level CO₂ Laser Irradiation
LLLT induces vasodilation and activates cellular metabolism, potentially benefiting skin health and recovery.
March 2019, Shanghai University of Traditional Chinese Medicine, School of Acupuncture and Massage, Shanghai, China; Shanghai Acupuncture and Meridian Research Center, Shanghai, China
Transcranial PBMT for Cognitive Impairment: A Review of Molecular Mechanisms and Potential Applications for Canine Cognitive Dysfunction (CCD)
Transcranial PBMT (tPBM) enhances mitochondrial ATP production, regulates ROS, reduces inflammation, and promotes neuroplasticity, which may improve cognitive function.
March 2022, Elemental Pet Vet, PLLC, Freeville, New York, USA; Chi University, Reddick, Florida, USA; Veterinary Surgical Center Rehabilitation, Vienna, Virginia, USA
Effects of Blue Light-Emitting Diodes (LEDs) on Burn Wound Healing via Photobiomodulation
Blue LED PBMT is a promising adjunct therapy for burn treatment.
November 2023, Graduate Program in Dentistry, State University of Paraíba, Campina Grande, Brazil.
Effects of Red and Green Light PBMT on Third-Degree Burn Healing
PBMT shows promise as an adjunct therapy for severe burn treatment.
February 2020, Graduate Program in Dentistry, State University of Paraíba, Campina Grande, Brazil.
Effects of PBMT and Metformin on Open Skin Wound Healing in a Non-Genetic Type 2 Diabetes Model
PBMT combined with Metformin effectively improved wound healing in diabetic patients.
April 2017, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Biology and Anatomy, Shahid Beheshti University of Medical Sciences.
Effects of PBMT on Angiogenesis in Rat Skin Wounds Using Various Light Sources
PBMT plays a crucial role in skin wound healing.
April 2007, University of São Paulo (USP), São Carlos School of Engineering, Brazil.
Mechanisms of PBMT in Induced Skin Wound Healing in Aged Rats: Time Course of Inflammatory and Healing Biomarkers
PBMT was found to shorten the initial inflammatory phase and accelerate the healing phase.
November 2017, University of Nove de Julho (UNINOVE), São Paulo, Brazil; University of Chapecó (UNOCHAPECÓ), Chapecó, Brazil.
Comparative Study of PBMT in Open Skin Wound Healing in Rats
PBMT has been shown to be an effective adjunct therapy for open skin wound healing.
December 2021, Federal University of Santa Catarina, Araranguá, Brazil.
Unlocking the Power of Light in Skin: A Comprehensive Review of PBMT
PBMT has applications in wrinkle reduction, scar treatment, and acne management.
April 2024, Ramón y Cajal University Hospital, Madrid, Spain; University of Florence, Italy.
PBMT Enhances the Migration of Surrounding Cells for Skin Regeneration
PBMT has been shown to promote skin regeneration and wound healing.
June 2020, Federal University of Minas Gerais, Brazil.
Effects of PBMT on Skin Graft Integration in Rats
PBMT was found to improve recovery and success rates in skin graft surgeries.
June 2020, Federal University of São Carlos, São Paulo, Brazil.
Molecular Evidence Review of PBMT
PBMT is effective for wrinkle reduction, skin elasticity improvement, and scar and wound healing.
May 2021, Sidra Medicine, Doha, Qatar.
PBMT for Reversing Signs of Skin Aging
PBMT increases collagen production, strengthens elastin fibers, improves skin elasticity, and reduces wrinkles.
July 2023, Christian Dior Perfumes, France; European LED Academy.
Use of LED Devices for Neck Wrinkle Improvement and Thyroid Safety
PBMT using LED devices effectively promotes collagen production, reduces wrinkles, and improves overall skin quality without negatively affecting thyroid function.
April 2021, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea.
Interaction Between PBMT and Guarana (Paullinia cupana) Extract: Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Effects
PBMT combined with Guarana extract induces antioxidant, anti-inflammatory, and anti-apoptotic effects, while promoting dermal fibroblast proliferation.
March 2020, Federal University of Santa Maria, Brazil.
PBMT Attenuates Cardiovascular Aging and Improves Longevity
PBMT improves blood circulation, collagen synthesis, and elastin production, making it a promising anti-aging therapy.
February 2023, National Institute on Aging, NIH, Baltimore, USA.
Application of Cell Therapy for Anti-Aging Facial Skin
PBMT has shown effectiveness in improving skin elasticity, reducing wrinkles, and enhancing skin tone.
July 2005, Lorestan University of Medical Sciences, Iran.
