Research With
Huelight Technology

Most improvements from HBOT were sustained, with some tests showing continued improvement nearly three months after the final HBOT session. This suggests that HBOT could be proposed as a disease-modifying treatment for mTBI-related persistent post-concussion syndrome (PPCS)

Department of Emergency and Hyperbaric Medicine, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA, 2019

The evidence presented in this review indicates that HBOT has potential for the treatment and prevention of various types of neurological damage

Molecular and Cellular Biology Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran, 2020

This study demonstrated that high-concentration oxygen supply increases blood oxygen saturation, accelerating brain activation from cognitive processes and enhancing arithmetic abilities. The effect of high-concentration oxygen becomes particularly significant when task difficulty increases, as oxygen demand rises accordingly

Department of Biomedical Science and Engineering, Biomedical Science and Technology Research Institute, Konkuk University, 2008

Rats with traumatic brain injury (TBI) showed increased BBB permeability, brain edema, lesion volume, and neurological dysfunction, indicating severe brain damage, all of which were significantly reduced by 2% H₂ treatment. Furthermore, the reduction in oxidative products and the increase in endogenous antioxidant enzyme activity in brain tissue suggest that…

Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China, 710032, 2010

Inhalation of H₂ gas at a non-combustible level during ischemia and reperfusion reduces infarct size without altering hemodynamic parameters, helping to prevent harmful left ventricular remodeling. Therefore, H₂ gas inhalation is a promising approach to mitigate ischemia-reperfusion injury associated with coronary artery reperfusion

2008, Keio University School of Medicine, Department of Cardiology, Tokyo 160-8582, Japan

The H₂ group showed no significant adverse effects and demonstrated improvements in oxygen saturation. Key findings included changes in relative signal intensity on MRI, which reflects the severity of the infarct area, improvements in NIHSS scores that clinically quantify stroke severity, and better physical therapy outcomes as measured by the…

2017, Department of Neurosurgery, Nishijima Hospital, Numazu City, Shizuoka, Japan

Adult male rats inhaled 2% hydrogen gas for 3 hours starting 1 hour after undergoing stabilized tibial fracture surgery. Cognitive assessments using fear conditioning and Y-maze tests revealed significant surgery-induced impairments, which were notably improved by H₂ treatment. This therapy reduced inflammatory cytokines (TNF-α, IL-1β, IL-6, HMGB1) in the serum…

2017, Department of Anesthesiology and Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, China, and Department of Respiratory and Critical Care Medicine

Hydrogen gas inhalation is an effective method to protect the brain of infants from post-hemorrhage effects that lead to brain atrophy, intellectual disability, and cerebral palsy

2011, Department of Physiology, School of Medicine, Loma Linda University, Loma Linda, CA 92354, USA

According to the study results, 67% hydrogen gas generated by water electrolysis could be a promising therapeutic strategy for improving cognitive outcomes related to global brain hypoxia-ischemia following cardiac arrest

2019, Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, California, USA

According to the study results, H₂ therapy improved survival rates, alleviated cognitive deficits, reduced histological damage in the hippocampus, and decreased Evans blue (EB) and water content. Additionally, H₂ therapy reduced the levels of TNF-α, IL-6, HMGB1, Nrf2, HO-1, ZO-1, and Occludin compared to the SAE group

2020, Department of Anesthesiology, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, People's Republic of China

Most neurological diseases are currently incurable, but these studies suggest the clinical potential of H₂ administration for their prevention, treatment, and mitigation. The potential mechanisms of H₂, including the cell signaling molecules and hormones responsible for preventing oxidative stress and inflammation, will also be discussed. Nevertheless, further investigation is needed…

2017, Biological Aging Process, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan

Our research findings suggest that (1) prolonged exposure to hydrogen gas is a simple, safe, and effective therapeutic approach to prevent memory loss in sepsis patients, and (2) short-term H₂ inhalation reduces neuroinflammation in brain regions associated with memory and increases the expression of nuclear factor erythroid 2-related factor 2…

2020, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP 14049-900, Brazil