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Brain

Gut Photobiomodulation Restores Cognitive Function

Conclusion
  • This study investigated the effects of brain–gut photobiomodulation (PBM) on restoring cognitive changes in mice subjected to chronic stress.
  • PBM treatment was administered for 6 minutes per day over 3 weeks, and it improved cognitive function by modulating Sirt1 levels and reducing neuroinflammation.
  • PBM was found to normalize Sirt1 levels in the hippocampus, regulate the composition of the gut microbiota, and reduce neuroinflammation, thereby ameliorating cognitive impairment induced by chronic stress (p < 0.05).